Exciting Discoveries Emerging in the Field of Psychedelics

Learn more about the science from our team and other industry experts.

Jama Psychiatry
Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder

"In the overall sample, 17 participants (71%) atweek 1 and 17 (71%) atweek 4 had a clinically significant response to the intervention (_50% reduction in GRID-HAMD score), and 14 participants (58%) atweek 1 and 13 participants (54%) atweek 4were in remission (_7 GRID-HAMD score)."

Elsevier B.V.
The Experimental effects of Psilocybin on symptoms of Anxiety and Depression: A meta-analysis

"Within-group effects at post-treatment and six-month follow-up showed large reductions in anxiety and depression symptoms with no evidence of publication bias. Qualitative assessment of risk of bias was more concerning, with high risk in several domains. High between-study heterogeneity suggests there may be systematic variation across the studies. Future meta-analyses should examine study features (e.g., psilocybin dose) as moderators of treatment effects. Effects of psilocybin on anxiety and depression were also evident."

Journal of Humanistic Psychology
Patient Experiences of Psilocybin-Assisted Psychotherapy: An Interpretative Phenomenological Analysis

The current study is the first qualitative study of participant experiences in psilocybin-assisted psychotherapy. Participants received a moderate dose of psilocybin and adjunctive psychotherapy with an emphasis on the process of meaning-making. The findings support the conclusion that psilocybin-assisted psychotherapy may provide an effective treatment for psychological distress in cancer patients.Implications for theory and treatment are discussed.

Journal of Psychopharmacology
Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial

Clinically significant anxiety and depression are common in patients with cancer, and are associated with poor psychiatric and medical outcomes. Historical and recent research suggests a role for psilocybin to treat cancer-related anxiety and depression. In conjunction with psychotherapy, single moderate-dose psilocybin produced rapid, robust and enduring anxiolytic and anti-depressant effects in patients with cancer-related psychological distress.

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